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Differential Phospho‐Signatures in Blood Cells Identify LRRK2 G2019S Carriers in Parkinson's Disease

BACKGROUND: The clinicopathological phenotype of G2019S LRRK2‐associated Parkinson's disease (L2PD) is similar to idiopathic Parkinson's disease (iPD), and G2019S LRRK2 nonmanifesting carriers (L2NMCs) are at increased risk for development of PD. With various therapeutic strategies in the...

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Detalles Bibliográficos
Autores principales: Garrido, Alicia, Santamaría, Enrique, Fernández‐Irigoyen, Joaquín, Soto, Marta, Simonet, Cristina, Fernández, Manel, Obiang, Donina, Tolosa, Eduardo, Martí, María‐José, Padmanabhan, Shalini, Malagelada, Cristina, Ezquerra, Mario, Fernández‐Santiago, Rubén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306798/
https://www.ncbi.nlm.nih.gov/pubmed/35049090
http://dx.doi.org/10.1002/mds.28927