Unifying Scheme for the Biosynthesis of Acyl‐Branched Sugars: Extended Substrate Scope of Thiamine‐Dependent Enzymes

Thiamine diphosphate (ThDP) dependent enzymes are useful catalysts for asymmetric C−C bond formation through benzoin‐type condensation reactions that result in α‐hydroxy ketones. A wide range of aldehydes and ketones can be used as acceptor substrates; however, the donor substrate range is mostly li...

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Detalles Bibliográficos
Autores principales: Steitz, Jan‐Patrick, Krug, Leonhard, Walter, Lydia, Hernández, Karel, Röhr, Caroline, Clapés, Pere, Müller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306805/
https://www.ncbi.nlm.nih.gov/pubmed/35092140
http://dx.doi.org/10.1002/anie.202113405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306805/
https://www.ncbi.nlm.nih.gov/pubmed/35092140
http://dx.doi.org/10.1002/anie.202113405

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