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Sphingosine‐1‐phosphate/TGF‐β axis drives epithelial mesenchymal transition in asthma‐like disease

BACKGROUND AND PURPOSE: Airway remodelling is a critical feature of chronic lung diseases. Epithelial‐mesenchymal transition (EMT) represents an important source of myofibroblasts, contributing to airway remodelling. Here, we investigated the sphingosine‐1‐phosphate (S1P) role in EMT and its involve...

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Detalles Bibliográficos
Autores principales: Riemma, Maria A., Cerqua, Ida, Romano, Barbara, Irollo, Elena, Bertolino, Antonio, Camerlingo, Rosa, Granato, Elisabetta, Rea, Giuseppina, Scala, Stefania, Terlizzi, Michela, Spaziano, Giuseppe, Sorrentino, Rosalinda, D'Agostino, Bruno, Roviezzo, Fiorentina, Cirino, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306821/
https://www.ncbi.nlm.nih.gov/pubmed/34825370
http://dx.doi.org/10.1111/bph.15754