Intrapulmonary Pharmacokinetic Modeling and Simulation of Cefiderocol, a Parenteral Siderophore Cephalosporin, in Patients With Pneumonia and Healthy Subjects

Cefiderocol is a siderophore cephalosporin for the treatment of infections caused by gram‐negative bacteria including carbapenem‐resistant strains. The aim of this study was to develop an intrapulmonary pharmacokinetic (PK) model of cefiderocol and assess the PK profile in lungs. An intrapulmonary P...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Nao, Katsube, Takayuki, Echols, Roger, Wajima, Toshihiro, Nicolau, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Pharmacokinetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306831/
https://www.ncbi.nlm.nih.gov/pubmed/34648652
http://dx.doi.org/10.1002/jcph.1986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306831/
https://www.ncbi.nlm.nih.gov/pubmed/34648652
http://dx.doi.org/10.1002/jcph.1986

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