Peptide‐Catalyzed Stereoselective Conjugate Addition Reaction of Aldehydes to C‐Substituted Maleimides

Catalytic stereoselective additions with maleimides are useful one‐step reactions to yield chiral succinimides, molecules that are widespread among therapeutically active compounds but challenging to prepare when the maleimide is C‐substituted. We present the tripeptide H‐Pro‐Pro‐Asp‐NHC(12)H(25) as...

Descripción completa

Detalles Bibliográficos
Autores principales: Vastakaite, Greta, Grünenfelder, Claudio E., Wennemers, Helma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306895/
https://www.ncbi.nlm.nih.gov/pubmed/35089626
http://dx.doi.org/10.1002/chem.202200215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306895/
https://www.ncbi.nlm.nih.gov/pubmed/35089626
http://dx.doi.org/10.1002/chem.202200215

Ejemplares similares