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Role of geochemical protoenzymes (geozymes) in primordial metabolism: specific abiotic hydride transfer by metals to the biological redox cofactor NAD(+)

Hydrogen gas, H(2), is generated in serpentinizing hydrothermal systems, where it has supplied electrons and energy for microbial communities since there was liquid water on Earth. In modern metabolism, H(2) is converted by hydrogenases into organically bound hydrides (H(–)), for example, the cofact...

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Detalles Bibliográficos
Autores principales: Henriques Pereira, Delfina P., Leethaus, Jana, Beyazay, Tugce, do Nascimento Vieira, Andrey, Kleinermanns, Karl, Tüysüz, Harun, Martin, William F., Preiner, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306933/
https://www.ncbi.nlm.nih.gov/pubmed/34923745
http://dx.doi.org/10.1111/febs.16329