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The severity of behavioural symptoms in FTD is linked to the loss of GABRQ‐expressing VENs and pyramidal neurons

AIMS: The loss of von Economo neurons (VENs) and GABA receptor subunit theta (GABRQ) containing neurons is linked to early changes in social–emotional cognition and is seen in frontotemporal dementia (FTD) due to C9orf72 repeat expansion. We investigate the vulnerability of VENs and GABRQ‐expressing...

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Detalles Bibliográficos
Autores principales: Gami‐Patel, Priya, Scarioni, Marta, Bouwman, Femke H., Boon, Baayla D. C., van Swieten, John C., Brain Bank, Netherlands, Rozemuller, Annemieke J. M., Smit, August B., Pijnenburg, Yolande A. L., Hoozemans, Jeroen J. M., Dijkstra, Anke A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306948/
https://www.ncbi.nlm.nih.gov/pubmed/35152451
http://dx.doi.org/10.1111/nan.12798