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Quercetin facilitates cell death and chemosensitivity through RAGE/PI3K/AKT/mTOR axis in human pancreatic cancer cells

The triggering of gemcitabine (GEM) drug resistance in pancreatic cancer by the receptor for advanced glycation end products (RAGE) has been demonstrated. Hence, finding a safe and effective adjuvant for preventing pancreatic cancer progression is imperative. Quercetin is a flavonoid that is abundan...

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Detalles Bibliográficos
Autores principales: Lan, Chieh-Yu, Chen, Sheng-Yi, Kuo, Chia-Wen, Lu, Chi-Cheng, Yen, Gow-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306979/
https://www.ncbi.nlm.nih.gov/pubmed/31590760
http://dx.doi.org/10.1016/j.jfda.2019.07.001