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A Modular Synthesis of Teraryl‐Based α‐Helix Mimetics, Part 3: Iodophenyltriflate Core Fragments Featuring Side Chains of Proteinogenic Amino Acids

Teraryl‐based α‐helix mimetics have proven to be useful compounds for the inhibition of protein‐protein interactions (PPI). We have developed a modular and flexible approach for the synthesis of teraryl‐based α‐helix mimetics using a benzene core unit featuring two leaving groups of differentiated r...

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Detalles Bibliográficos
Autores principales: Trobe, Melanie, Vareka, Martin, Schreiner, Till, Dobrounig, Patrick, Doler, Carina, Holzinger, Ella B., Steinegger, Andreas, Breinbauer, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9306992/
https://www.ncbi.nlm.nih.gov/pubmed/35910459
http://dx.doi.org/10.1002/ejoc.202101278