The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model

An active role of neuroinflammation and the NLRP3 inflammasome in Alzheimer's disease and related tauopathies is increasingly identified, supporting NLRP3 as an interesting therapeutic target. However, its effect on tau‐associated neurodegeneration, a key‐process in tauopathies, remains unknown...

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Detalles Bibliográficos
Autores principales: Stancu, Ilie Cosmin, Lodder, Chritica, Botella Lucena, Pablo, Vanherle, Sarah, Gutiérrez de Ravé, Manuel, Terwel, Dick, Bottelbergs, Astrid, Dewachter, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307007/
https://www.ncbi.nlm.nih.gov/pubmed/35174546
http://dx.doi.org/10.1002/glia.24160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307007/
https://www.ncbi.nlm.nih.gov/pubmed/35174546
http://dx.doi.org/10.1002/glia.24160

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