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The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model
An active role of neuroinflammation and the NLRP3 inflammasome in Alzheimer's disease and related tauopathies is increasingly identified, supporting NLRP3 as an interesting therapeutic target. However, its effect on tau‐associated neurodegeneration, a key‐process in tauopathies, remains unknown...
Autores principales: | Stancu, Ilie Cosmin, Lodder, Chritica, Botella Lucena, Pablo, Vanherle, Sarah, Gutiérrez de Ravé, Manuel, Terwel, Dick, Bottelbergs, Astrid, Dewachter, Ilse |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307007/ https://www.ncbi.nlm.nih.gov/pubmed/35174546 http://dx.doi.org/10.1002/glia.24160 |
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