Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) R47H Variant Causes Distinct Age‐ and Sex‐Dependent Musculoskeletal Alterations in Mice

Previous studies proposed the Triggering Receptor Expressed on Myeloid Cells 2 (TREM2), a receptor expressed in myeloid cells including microglia in brain and osteoclasts in bone, as a link between brain and bone disease. The TREM2 R47H variant is a known risk factor for Alzheimer's disease (AD...

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Detalles Bibliográficos
Autores principales: Essex, Alyson L., Huot, Joshua R., Deosthale, Padmini, Wagner, Alison, Figueras, Jorge, Davis, Azaria, Damrath, John, Pin, Fabrizio, Wallace, Joseph, Bonetto, Andrea, Plotkin, Lilian I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307075/
https://www.ncbi.nlm.nih.gov/pubmed/35575023
http://dx.doi.org/10.1002/jbmr.4572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307075/
https://www.ncbi.nlm.nih.gov/pubmed/35575023
http://dx.doi.org/10.1002/jbmr.4572

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