Dexmedetomidine Attenuates Ferroptosis-Mediated Renal Ischemia/Reperfusion Injury and Inflammation by Inhibiting ACSL4 via α2-AR

Ischemia-reperfusion (I/R) injury is a serious clinical pathology associated with acute kidney injury (AKI). Ferroptosis is non-apoptotic cell death that is known to contribute to renal I/R injury. Dexmedetomidine (Dex) has been shown to exert anti-inflammatory and organ protective effects. This stu...

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Detalles Bibliográficos
Autores principales: Tao, Wen-hui, Shan, Xi-sheng, Zhang, Jia-xin, Liu, Hua-yue, Wang, Bi-ying, Wei, Xiang, Zhang, Mian, Peng, Ke, Ding, Jun, Xu, Shang-xian, Li, Lin-gui, Hu, Jun-kai, Meng, Xiao-wen, Ji, Fu-hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307125/
https://www.ncbi.nlm.nih.gov/pubmed/35873574
http://dx.doi.org/10.3389/fphar.2022.782466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307125/
https://www.ncbi.nlm.nih.gov/pubmed/35873574
http://dx.doi.org/10.3389/fphar.2022.782466

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