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Influence of Germline BRCA Genotype on the Survival of Patients with Triple-Negative Breast Cancer

The presence of BRCA pathogenic variants (PV) in triple-negative breast cancer (TNBC) is associated with a distinctive genomic profile that makes the tumor particularly susceptible to DNA-damaging treatments. However, patients with BRCA PVs can develop treatment resistance through the appearance of...

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Detalles Bibliográficos
Autores principales: Villarreal-Garza, Cynthia, Ferrigno, Ana S., Aranda-Gutierrez, Alejandro, Frankel, Paul H., Ruel, Nora H., Fonseca, Alan, Narod, Steven, Chavarri-Guerra, Yanin, Sifuentes, Erika, Magallanes-Hoyos, Maria Cristina, Herzog, Josef, Castillo, Danielle, Alvarez-Gomez, Rosa M., Mohar-Betancourt, Alejandro, Weitzel, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307147/
https://www.ncbi.nlm.nih.gov/pubmed/35875314
http://dx.doi.org/10.1158/2767-9764.CRC-21-0099