‘Mechanistic insights into 5-lipoxygenase inhibition by active principles derived from essential oils of Curcuma species: Molecular docking, ADMET analysis and molecular dynamic simulation study

Inflammation is caused by a cascade of events, one of which is the metabolism of arachidonic acid, that begins with oxidation by the enzyme 5-lipoxygenase. 5-Lipoxygenase (5-LOX) plays an important role in the inflammation process by synthesizing leukotrienes and several lipid mediators and has emer...

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Detalles Bibliográficos
Autores principales: Gadnayak, Ayushman, Dehury, Budheswar, Nayak, Ananya, Jena, Sudipta, Sahoo, Ambika, Panda, Pratap Chandra, Ray, Asit, Nayak, Sanghamitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307165/
https://www.ncbi.nlm.nih.gov/pubmed/35867724
http://dx.doi.org/10.1371/journal.pone.0271956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307165/
https://www.ncbi.nlm.nih.gov/pubmed/35867724
http://dx.doi.org/10.1371/journal.pone.0271956

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