Epigenetic controls of Sonic hedgehog guarantee fidelity of epithelial adult stem cells trajectory in regeneration

Given that adult stem cells (ASCs) fuel homeostasis and healing by providing tissue-specific descendants, the fidelity of ASC fate determination is crucial for regeneration. Here, we established that an epigenetic control of epithelial ASC fate fidelity via Ezh2/H3K27me3 was indispensable for inciso...

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Detalles Bibliográficos
Autores principales: Yu, Fanyuan, Li, Feifei, Zheng, Liwei, Ye, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307244/
https://www.ncbi.nlm.nih.gov/pubmed/35867784
http://dx.doi.org/10.1126/sciadv.abn4977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307244/
https://www.ncbi.nlm.nih.gov/pubmed/35867784
http://dx.doi.org/10.1126/sciadv.abn4977

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