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The ER protein Creld regulates ER-mitochondria contact dynamics and respiratory complex 1 activity
Dynamic contacts are formed between endoplasmic reticulum (ER) and mitochondria that enable the exchange of calcium and phospholipids. Disturbed contacts between ER and mitochondria impair mitochondrial dynamics and are a molecular hallmark of Parkinson’s disease, which is also characterized by impa...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307246/ https://www.ncbi.nlm.nih.gov/pubmed/35867795 http://dx.doi.org/10.1126/sciadv.abo0155 |