Cargando…

Uncovering temporospatial sensitive TBI targeting strategies via in vivo phage display

The heterogeneous pathophysiology of traumatic brain injury (TBI) is a barrier to advancing diagnostics and therapeutics, including targeted drug delivery. We used a unique discovery pipeline to identify novel targeting motifs that recognize specific temporal phases of TBI pathology. This pipeline c...

Descripción completa

Detalles Bibliográficos
Autores principales: Martinez, Briana I., Mousa, Gergey Alzaem, Fleck, Kiera, MacCulloch, Tara, Diehnelt, Chris W., Stephanopoulos, Nicholas, Stabenfeldt, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307250/
https://www.ncbi.nlm.nih.gov/pubmed/35867794
http://dx.doi.org/10.1126/sciadv.abo5047