Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status

G-protein-coupled receptors (GPCR) are present at the cell surface in different conformational and oligomeric states. However, how these states impact GPCRs biological function and therapeutic targeting remains incompletely known. Here, we investigated this issue in living cells for the CC chemokine...

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Detalles Bibliográficos
Autores principales: Momboisse, Fanny, Nardi, Giacomo, Colin, Philippe, Hery, Melanie, Cordeiro, Nelia, Blachier, Simon, Schwartz, Olivier, Arenzana-Seisdedos, Fernando, Sauvonnet, Nathalie, Olivo-Marin, Jean-Christophe, Lagane, Bernard, Lagache, Thibault, Brelot, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307273/
https://www.ncbi.nlm.nih.gov/pubmed/35866628
http://dx.doi.org/10.7554/eLife.76281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307273/
https://www.ncbi.nlm.nih.gov/pubmed/35866628
http://dx.doi.org/10.7554/eLife.76281

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