Inhibition of Xanthine Oxidase Protects against Sepsis-Induced Acute Kidney Injury by Ameliorating Renal Hypoxia

Xanthine oxidase (XO) utilizes molecular oxygen as a substrate to convert purine substrates into uric acid, superoxide, and hydrogen peroxide, which is one of the main enzyme pathways to produce reactive oxygen species (ROS) during septic inflammation and oxidative stress. However, it is not clear w...

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Detalles Bibliográficos
Autores principales: Wang, Ting-ting, Du, Yi-wei, Wang, Wen, Li, Xiang-nan, Liu, Hong-bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307393/
https://www.ncbi.nlm.nih.gov/pubmed/35873795
http://dx.doi.org/10.1155/2022/4326695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307393/
https://www.ncbi.nlm.nih.gov/pubmed/35873795
http://dx.doi.org/10.1155/2022/4326695

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