Chlorpromazine and Promethazine (C+P) Reduce Brain Injury after Ischemic Stroke through the PKC-δ/NOX/MnSOD Pathway

Cerebral ischemia-reperfusion (I/R) incites neurologic damage through a myriad of complex pathophysiological mechanisms, most notably, inflammation and oxidative stress. In I/R injury, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) produces reactive oxygen species (ROS), which pro...

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Detalles Bibliográficos
Autores principales: Guo, Sichao, Li, Fengwu, Wills, Melissa, Yip, James, Wehbe, Alexandra, Peng, Changya, Geng, Xiaokun, Ding, Yuchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307415/
https://www.ncbi.nlm.nih.gov/pubmed/35873710
http://dx.doi.org/10.1155/2022/6886752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307415/
https://www.ncbi.nlm.nih.gov/pubmed/35873710
http://dx.doi.org/10.1155/2022/6886752

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