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RBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31

RNF31 (HOIP), RBCK1 (HOIL-1L), and SHARPIN are subunits of the linear ubiquitin chain assembly complex. Their function and specific molecular mechanisms in hepatocellular carcinoma (HCC) have not been reported previously. Here, we investigated the role of RNF31 and RBCK1 in HCC. We showed that RNF31...

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Detalles Bibliográficos
Autores principales: Chen, Xijun, Ye, Qing, Zhao, Wenxiu, Chi, Xiaoqin, Xie, Chengrong, Wang, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307510/
https://www.ncbi.nlm.nih.gov/pubmed/35869046
http://dx.doi.org/10.1038/s41420-022-01126-x