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Liver-specific deletion of miR-181ab1 reduces liver tumour progression via upregulation of CBX7

MiR-181 expression levels increased in hepatocellular carcinoma (HCC) compared to non-cancerous tissues. MiR-181 has been widely reported as a possible driver of tumourigenesis but also acts as a tumour suppressor. In addition, the miR-181 family regulates the development and function of immune and...

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Detalles Bibliográficos
Autores principales: Chen, Jinbiao, Zhao, Yang, Zhang, Fan, Li, Jia, Boland, Jade A., Cheng, Ngan Ching, Liu, Ken, Tiffen, Jessamy C., Bertolino, Patrick, Bowen, David G., Krueger, Andreas, Lisowski, Leszek, Alexander, Ian E., Vadas, Mathew A., El-Omar, Emad, Gamble, Jennifer R., McCaughan, Geoffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307539/
https://www.ncbi.nlm.nih.gov/pubmed/35867177
http://dx.doi.org/10.1007/s00018-022-04452-6