Triphasic developmentally guided protocol to generate retinal pigment epithelium from induced pluripotent stem cells

RPE tissues are derived from induced pluripotent stem cells (iPSCs) to model retinal diseases and as a replacement therapy for macular degeneration. Here, we developed a robust and efficient directed differentiation protocol to generate pure RPE cells that form a polarized monolayer. This protocol d...

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Detalles Bibliográficos
Autores principales: Sharma, Ruchi, Bose, Devika, Montford, Jair, Ortolan, Davide, Bharti, Kapil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307589/
https://www.ncbi.nlm.nih.gov/pubmed/35880133
http://dx.doi.org/10.1016/j.xpro.2022.101582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307589/
https://www.ncbi.nlm.nih.gov/pubmed/35880133
http://dx.doi.org/10.1016/j.xpro.2022.101582

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