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Assessing comparative importance of DNA sequence and epigenetic modifications on gene expression using a deep convolutional neural network
Gene expression is regulated at both transcriptional and post-transcriptional levels. DNA sequence and epigenetic modifications are key factors which regulate gene transcription. Understanding their complex interactions and their respective contributions to gene expression regulation remains a chall...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307602/ https://www.ncbi.nlm.nih.gov/pubmed/35891778 http://dx.doi.org/10.1016/j.csbj.2022.07.014 |