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Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases
The establishment of robust human brain organoids to model cerebellar diseases is essential to study new therapeutic strategies for cerebellum-associated disorders. Machado-Joseph disease (MJD) is a cerebellar hereditary neurodegenerative disease, without therapeutic options able to prevent the dise...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307606/ https://www.ncbi.nlm.nih.gov/pubmed/35869235 http://dx.doi.org/10.1038/s41598-022-16369-y |