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Establishment and characterization of human pluripotent stem cells-derived brain organoids to model cerebellar diseases

The establishment of robust human brain organoids to model cerebellar diseases is essential to study new therapeutic strategies for cerebellum-associated disorders. Machado-Joseph disease (MJD) is a cerebellar hereditary neurodegenerative disease, without therapeutic options able to prevent the dise...

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Detalles Bibliográficos
Autores principales: Brás, João, Henriques, Daniel, Moreira, Ricardo, Santana, Magda M., Silva-Pedrosa, Rita, Adão, Diana, Braz, Sandra, Álvaro, Ana Rita, de Almeida, Luís Pereira, Mendonça, Liliana S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307606/
https://www.ncbi.nlm.nih.gov/pubmed/35869235
http://dx.doi.org/10.1038/s41598-022-16369-y