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A male-specific doublesex isoform reveals an evolutionary pathway of sexual development via distinct alternative splicing mechanisms

The doublesex/mab-3 related transcription factor (Dmrt) genes regulate sexual development in metazoans. Studies of the doublesex (dsx) gene in insects, in particular Drosophila melanogaster, reveal that alternative splicing of dsx generates sex-specific Dsx isoforms underlying sexual differentiation...

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Detalles Bibliográficos
Autores principales: Han, Caihong, Peng, Qionglin, Su, Xiangbin, Xing, Limin, Ji, Xiaoxiao, Pan, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307624/
https://www.ncbi.nlm.nih.gov/pubmed/35869175
http://dx.doi.org/10.1038/s42003-022-03664-7