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A male-specific doublesex isoform reveals an evolutionary pathway of sexual development via distinct alternative splicing mechanisms
The doublesex/mab-3 related transcription factor (Dmrt) genes regulate sexual development in metazoans. Studies of the doublesex (dsx) gene in insects, in particular Drosophila melanogaster, reveal that alternative splicing of dsx generates sex-specific Dsx isoforms underlying sexual differentiation...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307624/ https://www.ncbi.nlm.nih.gov/pubmed/35869175 http://dx.doi.org/10.1038/s42003-022-03664-7 |