Modulating co-translational protein folding by rational design and ribosome engineering

Co-translational folding is a fundamental process for the efficient biosynthesis of nascent polypeptides that emerge through the ribosome exit tunnel. To understand how this process is modulated by the shape and surface of the narrow tunnel, we have rationally engineered three exit tunnel protein lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahn, Minkoo, Włodarski, Tomasz, Mitropoulou, Alkistis, Chan, Sammy H. S., Sidhu, Haneesh, Plessa, Elena, Becker, Thomas A., Budisa, Nediljko, Waudby, Christopher A., Beckmann, Roland, Cassaignau, Anaïs M. E., Cabrita, Lisa D., Christodoulou, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307626/
https://www.ncbi.nlm.nih.gov/pubmed/35869078
http://dx.doi.org/10.1038/s41467-022-31906-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307626/
https://www.ncbi.nlm.nih.gov/pubmed/35869078
http://dx.doi.org/10.1038/s41467-022-31906-z

Ejemplares similares