Antibody CDR amino acids underlying the functionality of antibody repertoires in recognizing diverse protein antigens

Antibodies recognize protein antigens with exquisite specificity in a complex aqueous environment, where interfacial waters are an integral part of the antibody–protein complex interfaces. In this work, we elucidate, with computational analyses, the principles governing the antibodies’ specificity a...

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Detalles Bibliográficos
Autores principales: Peng, Hung-Pin, Hsu, Hung-Ju, Yu, Chung-Ming, Hung, Fei-Hung, Tung, Chao-Ping, Huang, Yu-Chuan, Chen, Chi-Yung, Tsai, Pei-Hsun, Yang, An-Suei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307644/
https://www.ncbi.nlm.nih.gov/pubmed/35869245
http://dx.doi.org/10.1038/s41598-022-16841-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307644/
https://www.ncbi.nlm.nih.gov/pubmed/35869245
http://dx.doi.org/10.1038/s41598-022-16841-9

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