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Tumorigenic cell selection and substrate rigidity manipulation using 2D and 3D extracellular matrices

Soft fibrin gels are used to select tumorigenic cells and regulate the stemness and metastasis of colorectal cancer cells via mechanotransduction. This protocol details steps to produce two-dimensional (2D) and three-dimensional (3D) extracellular matrices for substrate rigidity manipulation and tum...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Ha, Wentao, Chang, Yuhan, Ge, Yutong, Wei, Xiaowei, Tan, Youhua, Jia, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307683/
https://www.ncbi.nlm.nih.gov/pubmed/35880125
http://dx.doi.org/10.1016/j.xpro.2022.101577