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Vanadium pentoxide induced oxidative stress and cellular senescence in human lung fibroblasts

Both environmental exposure to vanadium pentoxide (V(2)O(5), V(+5) for its ionic counterparts) and fibroblast senescence are associated with pulmonary fibrosis, but whether V(+5) causes fibroblast senescence remains unknown. We found in a dose-response study that 2–40 μM V(+5) caused human lung fibr...

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Detalles Bibliográficos
Autores principales: He, Xiaojia, Jarrell, Zachery R., Liang, Yongliang, Ryan Smith, Matthew, Orr, Michael L., Marts, Lucian, Go, Young-Mi, Jones, Dean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307685/
https://www.ncbi.nlm.nih.gov/pubmed/35870339
http://dx.doi.org/10.1016/j.redox.2022.102409