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Blockade of CD47 enhances the antitumor effect of macrophages in renal cell carcinoma through trogocytosis

Immune checkpoint inhibitors and vascular endothelial growth factor receptor tyrosine kinase inhibitors (VEGFR TKIs) are mainstream treatments for renal cell carcinoma (RCC). Both T cells and macrophages infiltrate the tumor microenvironment of RCC. CD47, an immune checkpoint of macrophages, transmi...

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Detalles Bibliográficos
Autores principales: Park, Ha-Ram, Kim, Seong-Eun, Keam, Bhumsuk, Chung, Hyewon, Seok, Seung Hyeok, Kim, Soyeon, Kim, Miso, Kim, Tae Min, Doh, Junsang, Kim, Dong-Wan, Heo, Dae Seog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307775/
https://www.ncbi.nlm.nih.gov/pubmed/35869130
http://dx.doi.org/10.1038/s41598-022-16766-3