A multi-omic dissection of super-enhancer driven oncogenic gene expression programs in ovarian cancer

The human genome contains regulatory elements, such as enhancers, that are often rewired by cancer cells for the activation of genes that promote tumorigenesis and resistance to therapy. This is especially true for cancers that have little or no known driver mutations within protein coding genes, su...

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Detalles Bibliográficos
Autores principales: Kelly, Michael R., Wisniewska, Kamila, Regner, Matthew J., Lewis, Michael W., Perreault, Andrea A., Davis, Eric S., Phanstiel, Douglas H., Parker, Joel S., Franco, Hector L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307778/
https://www.ncbi.nlm.nih.gov/pubmed/35869079
http://dx.doi.org/10.1038/s41467-022-31919-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307778/
https://www.ncbi.nlm.nih.gov/pubmed/35869079
http://dx.doi.org/10.1038/s41467-022-31919-8

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