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A multi-omic dissection of super-enhancer driven oncogenic gene expression programs in ovarian cancer
The human genome contains regulatory elements, such as enhancers, that are often rewired by cancer cells for the activation of genes that promote tumorigenesis and resistance to therapy. This is especially true for cancers that have little or no known driver mutations within protein coding genes, su...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307778/ https://www.ncbi.nlm.nih.gov/pubmed/35869079 http://dx.doi.org/10.1038/s41467-022-31919-8 |