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Maternal stress induced endoplasmic reticulum stress and impaired pancreatic islets’ insulin secretion via glucocorticoid receptor upregulation in adult male rat offspring

Exposure to perinatal (prenatal and/or postnatal) stress is considered as a risk factor for metabolic disorders in later life. Accordingly, this study aimed to investigate the perinatal stress effects on the pancreatic endoplasmic reticulum (ER) stress induction, insulin secretion impairment and WFS...

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Detalles Bibliográficos
Autores principales: Salimi, Mina, Eskandari, Farzaneh, Binayi, Fateme, Eliassi, Afsaneh, Ghanbarian, Hossein, Hedayati, Mehdi, Fahanik-babaei, Javad, Eftekhary, Mohamad, Keyhanmanesh, ‬Rana, Zardooz, Homeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307850/
https://www.ncbi.nlm.nih.gov/pubmed/35869151
http://dx.doi.org/10.1038/s41598-022-16621-5