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Microbiota-Derived Propionate Modulates Megakaryopoiesis and Platelet Function

Rheumatoid arthritis (RA) is associated with an increased risk for cardiovascular events driven by abnormal platelet clotting effects. Platelets are produced by megakaryocytes, deriving from megakaryocyte erythrocyte progenitors (MEP) in the bone marrow. Increased megakaryocyte expansion across comm...

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Detalles Bibliográficos
Autores principales: Dürholz, Kerstin, Schmid, Eva, Frech, Michael, Azizov, Vugar, Otterbein, Nadine, Lucas, Sébastien, Rauh, Manfred, Schett, Georg, Bruns, Heiko, Zaiss, Mario M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307893/
https://www.ncbi.nlm.nih.gov/pubmed/35880182
http://dx.doi.org/10.3389/fimmu.2022.908174