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MicroRNA-466 and microRNA-200 increase endothelial permeability in hyperglycemia by targeting Claudin-5

Endothelial cell (EC) permeability is essential to vascular homeostasis in diabetes. MicroRNAs are critical gene regulators whose roles in the EC permeability have yet to be characterized. This study aims to examine the change in cell permeability induced by miR-200 and miR-466 in ECs. Human aortic...

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Detalles Bibliográficos
Autores principales: Kujawa, Marisa, O’Meara, Megan, Li, Hainan, Xu, Liping, Meda Venkata, Sai Pranathi, Nguyen, Huong, Minjares, Morgan, Zhang, Kezhong, Wang, Jie-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307898/
https://www.ncbi.nlm.nih.gov/pubmed/35892090
http://dx.doi.org/10.1016/j.omtn.2022.07.002