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Toll-like Receptor 9 Promotes Initiation of Gastric Tumorigenesis by Augmenting Inflammation and Cellular Proliferation

BACKGROUND & AIMS: Gastric cancer (GC) is strongly linked with chronic gastritis after Helicobacter pylori infection. Toll-like receptors (TLRs) are key innate immune pathogenic sensors that mediate chronic inflammatory and oncogenic responses. Here, we investigated the role of TLR9 in the patho...

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Detalles Bibliográficos
Autores principales: Tang, Ke, McLeod, Louise, Livis, Thaleia, West, Alison C., Dawson, Ruby, Yu, Liang, Balic, Jesse J., Chonwerawong, Michelle, Wray-McCann, Georgie, Oshima, Hiroko, Oshima, Masanobu, Deswaerte, Virginie, Ferrero, Richard L., Jenkins, Brendan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9307956/
https://www.ncbi.nlm.nih.gov/pubmed/35716851
http://dx.doi.org/10.1016/j.jcmgh.2022.06.002