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Competitive SNP-LAMP probes for rapid and robust single-nucleotide polymorphism detection
In this work, we developed a simple and robust assay to rapidly detect SNPs in nucleic acid samples. Our approach combines loop-mediated isothermal amplification (LAMP)-based target amplification with fluorescent probes to detect SNPs with high specificity. A competitive “sink” strand preferentially...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308130/ https://www.ncbi.nlm.nih.gov/pubmed/35880021 http://dx.doi.org/10.1016/j.crmeth.2022.100242 |