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Computational framework for single-cell spatiotemporal dynamics of optogenetic membrane recruitment

We describe a modular computational framework for analyzing cell-wide spatiotemporal signaling dynamics in single-cell microscopy experiments that accounts for the experiment-specific geometric and diffractive complexities that arise from heterogeneous cell morphologies and optical instrumentation....

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Detalles Bibliográficos
Autores principales: Kuznetsov, Ivan A., Berlew, Erin E., Glantz, Spencer T., Hannanta-Anan, Pimkhuan, Chow, Brian Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308134/
https://www.ncbi.nlm.nih.gov/pubmed/35880018
http://dx.doi.org/10.1016/j.crmeth.2022.100245