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Learning what not to select for in antibody drug discovery

Identifying antibodies with high affinity and target specificity is crucial for drug discovery and development; however, filtering out antibody candidates with nonspecific or polyspecific binding profiles is also important. In this issue of Cell Reports Methods, Saksena et al. report a computational...

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Detalles Bibliográficos
Autores principales: Gao, Beichen, Han, Jiami, Reddy, Sai T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308151/
https://www.ncbi.nlm.nih.gov/pubmed/35880020
http://dx.doi.org/10.1016/j.crmeth.2022.100258