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Miniaturized and multiplexed high-content screening of drug and immune sensitivity in a multichambered microwell chip

Here, we present a methodology based on multiplexed fluorescence screening of two- or three-dimensional cell cultures in a newly designed multichambered microwell chip, allowing direct assessment of drug or immune cell cytotoxic efficacy. We establish a framework for cell culture, formation of tumor...

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Detalles Bibliográficos
Autores principales: Sandström, Niklas, Carannante, Valentina, Olofsson, Karl, Sandoz, Patrick A., Moussaud-Lamodière, Elisabeth L., Seashore-Ludlow, Brinton, Van Ooijen, Hanna, Verron, Quentin, Frisk, Thomas, Takai, Madoka, Wiklund, Martin, Östling, Päivi, Önfelt, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308168/
https://www.ncbi.nlm.nih.gov/pubmed/35880015
http://dx.doi.org/10.1016/j.crmeth.2022.100256