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Evaluation of the effect of perioperative administration of S(+)-ketamine hydrochloride injection for postoperative acute pain in children: study protocol for a prospective, multicenter, randomized, open-label, parallel-group, pragmatic clinical trial

BACKGROUND: Inadequate postoperative pain management increases the risk of adverse events after the surgery and aggressive perioperative pain prevention has both short-term and long-term benefits. S(+)-ketamine is an N-methyl-D-aspartic acid (NMDA) receptor antagonist with a strong analgesic effect...

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Detalles Bibliográficos
Autores principales: Wang, Hong, Duan, Chongyang, Zhang, Jianmin, Qu, Shuangquan, Sun, Ying, Zhou, Lizhi, Yang, Lujia, Lan, Chen, Mi, Weidong, Chen, Pingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308221/
https://www.ncbi.nlm.nih.gov/pubmed/35870990
http://dx.doi.org/10.1186/s13063-022-06534-z