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Evaluation of the effect of perioperative administration of S(+)-ketamine hydrochloride injection for postoperative acute pain in children: study protocol for a prospective, multicenter, randomized, open-label, parallel-group, pragmatic clinical trial
BACKGROUND: Inadequate postoperative pain management increases the risk of adverse events after the surgery and aggressive perioperative pain prevention has both short-term and long-term benefits. S(+)-ketamine is an N-methyl-D-aspartic acid (NMDA) receptor antagonist with a strong analgesic effect...
Autores principales: | Wang, Hong, Duan, Chongyang, Zhang, Jianmin, Qu, Shuangquan, Sun, Ying, Zhou, Lizhi, Yang, Lujia, Lan, Chen, Mi, Weidong, Chen, Pingyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308221/ https://www.ncbi.nlm.nih.gov/pubmed/35870990 http://dx.doi.org/10.1186/s13063-022-06534-z |
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