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Widespread alterations in microRNA biogenesis in human Huntington’s disease putamen
Altered microRNA (miRNA) expression is a common feature of Huntington’s disease (HD) and could participate in disease onset and progression. However, little is known about the underlying causes of miRNA disruption in HD. We and others have previously shown that mutant Huntingtin binds to Ago2, a cen...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308264/ https://www.ncbi.nlm.nih.gov/pubmed/35869509 http://dx.doi.org/10.1186/s40478-022-01407-7 |