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Widespread alterations in microRNA biogenesis in human Huntington’s disease putamen

Altered microRNA (miRNA) expression is a common feature of Huntington’s disease (HD) and could participate in disease onset and progression. However, little is known about the underlying causes of miRNA disruption in HD. We and others have previously shown that mutant Huntingtin binds to Ago2, a cen...

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Detalles Bibliográficos
Autores principales:	Petry, Serena, Keraudren, Rémi, Nateghi, Behnaz, Loiselle, Andréanne, Pircs, Karolina, Jakobsson, Johan, Sephton, Chantelle, Langlois, Mélanie, St-Amour, Isabelle, Hébert, Sébastien S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308264/ https://www.ncbi.nlm.nih.gov/pubmed/35869509 http://dx.doi.org/10.1186/s40478-022-01407-7

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