Sex-biased and parental allele-specific gene regulation by KDM6A

BACKGROUND: KDM6A is a demethylase encoded by a gene with female-biased expression due to escape from X inactivation. Its main role is to facilitate gene expression through removal of the repressive H3K27me3 mark, with evidence of some additional histone demethylase-independent functions. KDM6A muta...

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Detalles Bibliográficos
Autores principales: Ma, Wenxiu, Fang, He, Pease, Nicolas, Filippova, Galina N., Disteche, Christine M., Berletch, Joel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308343/
https://www.ncbi.nlm.nih.gov/pubmed/35871105
http://dx.doi.org/10.1186/s13293-022-00452-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308343/
https://www.ncbi.nlm.nih.gov/pubmed/35871105
http://dx.doi.org/10.1186/s13293-022-00452-0

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