Epigenetic silencing and tumor suppressor gene of HAND2 by targeting ERK signaling in colorectal cancer

BACKGROUND: The screening biomarkers for early detection of colorectal cancer (CRC) is lacking. The aim is to identify epigenetic silenced genes and clarify its roles and underlying mechanism in CRC. We conducted integrative analyses of epigenome-wide Human Methylation 450 K arrays and transcriptome...

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Detalles Bibliográficos
Autores principales: Yuan, Zixu, Yu, Xihu, Chen, Wenle, Chen, Daici, Cai, Jian, Jiang, Yingming, Liu, Xiaoxia, Wu, Zhijie, Wang, Lei, Grady, William M., Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308366/
https://www.ncbi.nlm.nih.gov/pubmed/35870943
http://dx.doi.org/10.1186/s12964-022-00878-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308366/
https://www.ncbi.nlm.nih.gov/pubmed/35870943
http://dx.doi.org/10.1186/s12964-022-00878-4

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