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Investigation of single‐nucleotide polymorphisms in the NR3C1a glucocorticoid receptor gene in Cocker Spaniels with primary immune thrombocytopenia

BACKGROUND: In dogs, 6 single‐nucleotide polymorphisms (SNPs) have been described in the glucocorticoid receptor gene NR3C1a, 2 of which were nonsynonymous SNPs in exons 2 and 8. The clinical importance of these SNPs is unknown. OBJECTIVES: To investigate whether SNPs in NR3C1a are associated with c...

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Detalles Bibliográficos
Autores principales: Tayler, Sarah, Hazuchova, Katarina, Riddle, Anna, Swann, James W., Glanemann, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308442/
https://www.ncbi.nlm.nih.gov/pubmed/35689373
http://dx.doi.org/10.1111/jvim.16468